Biology
Grade-8
Easy
Question
For a gene to be expressed, ___ must bind to the gene's ___, a specific sequence of nucleotides at one end of the gene, thus initiating transcription.
- DNA polymerase, promoter
- DNA polymerase, operator
- RNA polymerase, promoter
- RNA polymerase, operator
Hint:
The central dogma of molecular biology: DNA → RNA → protein.
The correct answer is: RNA polymerase, promoter
A promoter, as related to genomics, is a region of DNA upstream of a gene where relevant proteins (such as RNA polymerase and transcription factors) bind to initiate the transcription of that gene. The resulting transcription produces an RNA molecule (such as mRNA).
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