Biology
Grade-10
Easy
Question
Which of the following does not belong to the citric acid cycle?
- Dehydrogenation
- Acetylation
- Oxidative phosphorylation
- Decarboxylation
Hint:
Acetylation is a process that is not a part of the citric acid cycle as dehydrogenation occurs 4 times in the cycle, decarboxylation occurs in two steps and Oxidative phosphorylation is the fourth step.
The correct answer is: Oxidative phosphorylation
- The dehydrogenation reaction occurs four times in Kreb's cycle, as follows: alpha-ketoglutarate isocitrate (NADH is formed), succinyl Co-A to alpha-ketoglutarate (NADH is formed), Succinate to Fumarate (FADH2 formation), and Oxaloacetate to malate (NADH is formed).
- Decarboxylation happens in two phases in the Krebs cycle. During the conversion of isocitrate to -ketoglutarate, the first oxidative decarboxylation occurs. Isocitrate dehydrogenase catalyzes this process.
- The second oxidative decarboxylation occurs when alpha-ketoglutarate is converted to succinyl-coenzyme A by alpha-ketoglutarate dehydrogenase.
- The fourth step of cellular respiration, oxidative phosphorylation, generates the majority of the energy.
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