Chemistry-
General
Easy
Question
In the Hofmann rearrangement an unsubstituted amide is treated with sodium hydroxide and bromine to give a primary amine that has one carbon lesser than starting amide.
General reaction :
Mechanism :
If the migrating group is chiral then its configuration is retained. Electron releasing effects in the migrating group increases reactivity of Hofmann rearrangement.
Which of the following compound(s) cannot give Hoffmann rearrangement :
The correct answer is:
Hoffmann rearrangement is shown by 1
amide only.
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