Biology
General
Easy
Question
Genetic equilibrium refers to phenomenon that
- The traits remains constant in a population
- The total genes remains constant in a population
- The total genes keeps on varying in a population
- Traits keeps on varying in a population
The correct answer is: The total genes remains constant in a population
Hardy-Weinberg Principle
It was proposed by GH Hardy an English mathematician and W Weinberg a German physician independently in 1908
(i) It describes a theoretical situation in which a population is undergoing no evolutionary change. This is called genetic or Hardy-Weinberg equilibrium
(ii) It can be expressed as or
(iii) Evolution occurs when the genetic equilibrium is up set (evolution is a departure from Hardy-Weinberg equilibrium principle)
The sum of total of Allelic frequency
or
Where, homozygous dominant individuals
frequency of dominant allele
homozygous recessive individuals
frequency of recessive allele
heterozygous individuals
Realize that (three are only 2 alleles)
(these are the only genotypes)
Example An investigator has determined by the inspection that 16% of a human population has a recessive trait. Using this information, we can calculate all the genotypes and allele frequencies for the population, provided the conditions for Hardy-Weinberg equilibrium are met
Given are homozygous recessive individuals
Therefore,
frequency of recessive allele
frequency of dominant allele
or 36% are homozygous dominant individuals
are heterozygous individuals
Or
Thus, 84% (36+48) have the dominant phenotype
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