Biology
Grade-10
Easy

Question

In the United States, one in every 10,000 new-borns is born with phenylketonuria (PKU), a metabolic condition caused by a recessive gene. What percentage of the human population is likely to carry the PKU allele?

  1. Approximately 0.2
  2. Approximately 0.02
  3. Approximately 0.19
  4. Approximately 0.98

hintHint:

Approximately 0.02

The correct answer is: Approximately 0.02


    This is by Hardy-Weinberg principle.
    p^2 + 2pq + q^2 = 1
    p^2 = dominant homozygous frequency (AA)
    2pq = heterozygous frequency (Aa)
    q^2 = recessive homozygous frequency (aa)

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