Question
Nitrous acid is a __________ agent.
Alkylating agent.
Deaminating agent.
Hydroxylating agent.
None of the above
Alkylating agent.
Deaminating agent.
Hydroxylating agent.
None of the above
Hint:
Nitrous acid converts cytosine to uracil and ammonia.
The correct answer is: Deaminating agent.
- Nitrous acid is a deaminating agent
- The deamination is the process of removal of an amino group
- In DNA, the deaminating agent causes removal of nitrogen containing groups (in bases)
- Deamination of bases causes conversion of one base to another base. Example: Cytosine (pyrimidine) is converted to uracil (purine) and ammonia
- The substitution of a pyrimidine to a purine causes change in the base pairing during subsequent replication and transcription process
Nitrous acid also converts adenine to hypoxanthine and guanine to xanthine
Related Questions to study
DNA is sensitive to temperatures above _______.
- PCR was discovered by Kary Mullis
- Various forms of PCR are available which are all based on the basic three steps
- Besides replication, PCR can also be used in diagnosis, modification of genetic material, paternity testing and many more
DNA is sensitive to temperatures above _______.
- PCR was discovered by Kary Mullis
- Various forms of PCR are available which are all based on the basic three steps
- Besides replication, PCR can also be used in diagnosis, modification of genetic material, paternity testing and many more
Ionizing radiations include:
- Mutagens are the factors that cause mutation
- Physical mutagens include ionizing radiations, high concentration of carbon dioxide, etc
Ionizing radiations include:
- Mutagens are the factors that cause mutation
- Physical mutagens include ionizing radiations, high concentration of carbon dioxide, etc
Generally, the mutations are:
- In harmful mutation, due to insertion or deletion of a base the resulting protein synthesis become faulty
- In silent mutation, the alteration in base sequence is such that the final protein is not changed
Generally, the mutations are:
- In harmful mutation, due to insertion or deletion of a base the resulting protein synthesis become faulty
- In silent mutation, the alteration in base sequence is such that the final protein is not changed
Which of the following base analogs exhibit tautomerism?
- Base analogues have structure similar to the common bases (Adenine, guanine, cytosine and thymine)
- 5bromouracil is the base analogue for thymine
Which of the following base analogs exhibit tautomerism?
- Base analogues have structure similar to the common bases (Adenine, guanine, cytosine and thymine)
- 5bromouracil is the base analogue for thymine
Point Mutation is caused by:
- Point mutation can be caused due to substitution by a base analogue or due to exposure to ionizing radiations as well
- Point mutation can also be due to deletion or insertion of a base pair
Point Mutation is caused by:
- Point mutation can be caused due to substitution by a base analogue or due to exposure to ionizing radiations as well
- Point mutation can also be due to deletion or insertion of a base pair
Examples of base analogs are ________.
- Base analogues are naturally occurring molecules having similar structure to common bases
- 5BU has structure similar to thymine
- 2aminopurine has structure similar to purine
Examples of base analogs are ________.
- Base analogues are naturally occurring molecules having similar structure to common bases
- 5BU has structure similar to thymine
- 2aminopurine has structure similar to purine
Alkyl bases are induced in DNA by which chemical mutagen?
- The alkylating agents helps in crosslinking of DNA which cannot replicate
- Other mechanism is by replacing hydrogen atoms of DNA with alkyl groups which cannot be repaired by the cell
Alkyl bases are induced in DNA by which chemical mutagen?
- The alkylating agents helps in crosslinking of DNA which cannot replicate
- Other mechanism is by replacing hydrogen atoms of DNA with alkyl groups which cannot be repaired by the cell
Base analogs are which type of mutagens?
- Bases are classified into purine and pyrimidine
- Purine include adenine and guanine which are two ringed structures
- Pyrimidine include thymine and uracil which are single ringed structures
Base analogs are which type of mutagens?
- Bases are classified into purine and pyrimidine
- Purine include adenine and guanine which are two ringed structures
- Pyrimidine include thymine and uracil which are single ringed structures
Ionizing radiation causes ___________.
- Ionizing radiations have shorter wavelength but high energy
- Ionizing radiations cause single strand break or crosslinking
Ionizing radiation causes ___________.
- Ionizing radiations have shorter wavelength but high energy
- Ionizing radiations cause single strand break or crosslinking
If the mutation occurs in the non-functional part of DNA, then these mutations may remain as _________.
- Silent mutation does not affect the individual since the change in the nucleic acid sequence doe not alter the amino acid produced.
If the mutation occurs in the non-functional part of DNA, then these mutations may remain as _________.
- Silent mutation does not affect the individual since the change in the nucleic acid sequence doe not alter the amino acid produced.
Mutations are mainly responsible for:
- Not all mutations are harmful
- Some mutations are silent, having no effect
- Development of lactose tolerance is an example for beneficial mutation
Mutations are mainly responsible for:
- Not all mutations are harmful
- Some mutations are silent, having no effect
- Development of lactose tolerance is an example for beneficial mutation
_______ is the most mutagenic among UV rays.
- UV B and UV C have mutagenic effects
- The UV C radiations are filtered by the atmosphere
- Transition mutation is caused by UV C
_______ is the most mutagenic among UV rays.
- UV B and UV C have mutagenic effects
- The UV C radiations are filtered by the atmosphere
- Transition mutation is caused by UV C
__________is the degree by which differences are seen in parents and their off-springs.
- No two individual is alike due to variation
- Variation is caused due to combination of paternal and maternal genes
- Environmental factors also can influence variation in some cases
__________is the degree by which differences are seen in parents and their off-springs.
- No two individual is alike due to variation
- Variation is caused due to combination of paternal and maternal genes
- Environmental factors also can influence variation in some cases
Physical mutagens include:
- Mutation cause change in DNA sequence
- Not all mutations are harmful
- Some mutations are beneficial to survive, while some mutations may not produce any effect
Physical mutagens include:
- Mutation cause change in DNA sequence
- Not all mutations are harmful
- Some mutations are beneficial to survive, while some mutations may not produce any effect
Mutation occurs at the time of:
- Mutation can be due to genetic or environmental factors
- The cause of mutation is called mutagen
- The individual affected is called mutant
- Not all mutations are harmful
Mutation occurs at the time of:
- Mutation can be due to genetic or environmental factors
- The cause of mutation is called mutagen
- The individual affected is called mutant
- Not all mutations are harmful