science
Grade-11
Easy

Question

What is the name of the protein that is not normal in people with sickle-cell disease?

  1. Mucus
  2. Clotting protein
  3. Karyotype
  4. Hemoglobin

hintHint:

Protein present in red blood cells.

The correct answer is: Hemoglobin


    Red blood cells contain a protein called hemoglobin which is necessary for gaseous exchange. Individuals affected with sickle cell anemia posses an abnormal type of hemoglobin called "S" hemoglobin.
    Normal RBCs are disc shaped, while the RBCs of patients with sickle cell anemia posses sickle shape attributing to the abnormal hemoglobin. The "S" hemoglobin causes the RBC to become rigid and become sickle shaped, thereby reducing the surface area of the cell.

    • Red blood cells contain a protein called hemoglobin
    • Sickle cell anemia patients will posses abnormal "S" hemoglobin
    • Clotting factors are present in plasma

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