Question
Which disease or disorder is caused by the inheritance of two mutated alleles?
- Down Syndrome
- Colorblindness
- Cystic fibrosis
- Hemophilia
Hint:
Example of an autosomal recessive disorder.
The correct answer is: Cystic fibrosis
Cystic fibrosis is a medical condition where in the individual secrets thick mucus secretion obstructing respiratory pathway. It is an autosomal recessive disorder- mutation of both the copies of the gene inside a cell. As a result, the person has two mutated alleles. Gene responsible for this disease is CFTR gene.
Down syndrome comes under chromosomal disorder (change in structure of chromosome), hemophilia is caused due to alteration of single gene in chromosome X and color blindness is autosomal dominant disorder- one copy of altered gene is sufficient to cause the disease.
- Cystic fibrosis results in breathing disorder of the affected individual due to increased thick mucus secretion
- The disorder is caused due to alteration in CFRT gene
- It is a type of autosomal recessive disorder, having both copies of gene altered in a cell
- Other disorders mentioned are not autosomal recessive in nature
Related Questions to study
Which of the following is NOT caused by a gene mutation?
it is an example of chromosomal disorder.
Which of the following is NOT caused by a gene mutation?
it is an example of chromosomal disorder.
Which of the following is NOT a chromosomal disorder?
others are example of chromosomal disorders.
Which of the following is NOT a chromosomal disorder?
others are example of chromosomal disorders.
Which of the following is a sex-linked disorder?
it is a sex-linked recessive disorder.
The abnormal gene responsible for hemophilia a carried on the X chromosome.
Which of the following is a sex-linked disorder?
it is a sex-linked recessive disorder.
The abnormal gene responsible for hemophilia a carried on the X chromosome.
Which of the following has normal sex chromosomes?
it occurs due to an extra autosome hence, sex chromosomes are not affected.
Which of the following has normal sex chromosomes?
it occurs due to an extra autosome hence, sex chromosomes are not affected.
Name the scientist who discovered the law of heredity:
gregor mendel discovered the law of heredity.
Name the scientist who discovered the law of heredity:
gregor mendel discovered the law of heredity.
A gamete contains which of the following?
each gamete receives single allele of a gene.
A gamete contains which of the following?
each gamete receives single allele of a gene.
All types of mutations are transferable among generations.
Germ-line mutations occur in gametes which can be inherited while, somatic mutations cannot be inherited.
All types of mutations are transferable among generations.
Germ-line mutations occur in gametes which can be inherited while, somatic mutations cannot be inherited.
Mark the INCORRECT statement about mutation?
mutation is not predestined.
It occurs when DNA is damaged or an error occurs in a DNA.
Mark the INCORRECT statement about mutation?
mutation is not predestined.
It occurs when DNA is damaged or an error occurs in a DNA.
Damage and errors in DNA cause___________.
damage and errors in DNA causes mutation.
Damage and errors in DNA cause___________.
damage and errors in DNA causes mutation.
